Biopharmaceuticals > Research
Research groups in Protein Medicinal Chemistry
- We use chemical entities to explore biology. Our current interests include novel peptido-mimetic foldamers, macrocyclic HDAC inhibitors and quorum sensing modulators, as well as lysine deacylase substrate specificity.
- Using a combination of synthetic amino acids and spectroscopic approaches, we focus on the function and pharmacology of a therapeutically relevant class of membrane proteins called ion channels.
- We combine chemistry and biology to study therapeutically relevant proteins. This entails developing inhibitors of protein–protein interactions and studying proteins using semi-synthesis and unnatural mutagenesis.